Why did my seizure start now? Influence of lesion connectivity and genetic etiology on rates of seizure onset in focal epilepsy; Macdonald-Laurs et al. 2024
Presentation by Dr. Tsalouchidou
00:00: Introduction
01:13: Key points about larger lesions being associated with earlier age onset.
03:00:Â Anatomical and functional network localization and connectivity analysis.
05:00: Functional connectivity and its impact on seizure onset.
07:00: Analysis of key findings and interpretations.
09:00: Strengths of the study, including the homogeneous cohort and comprehensive review.
10:00: Specific cohort of patients with severe onset in childhood.
Discussion
00:00:Â Influence of lesion connectivity and genetic etiology on seizure onset.
01:00:Â Development of epileptic networks.
02:00:Â Impact of lesion size and location.
03:00:Â Role of genetic variants.
07:00: Take home messages.
Laser Ablation of Periventricular Nodular Heterotopia for Medically Refractory Epilepsy; McCormack et al. 2024
Presentation by Dr. Irina Oane
00:00: Introduction
01:38: Variables Predicting Good Surgical Outcomes
02:58: Challenges in Treating Patients
04:00: Surgical Approaches and Methods
05:11: Research Questions and Study Design
06:45: Statistical Analysis and Outcomes
08:40: Follow-up and Complications
Discussion
00:00:Â Laser Ablation for Ventricular Nodular Heterotopia
02:00: Seizure Reduction Outcomes
03:00:Â Comparison with Traditional Surgery
05:00: Minimally Invasive Nature of Laser Ablation
07:00:Â Extrapolation to Other Etiologies
15:00:Â Final remarks